Turkish Stroke Research and Clinical Trials Network

The Official Network of Stroke Researchers under the guidance of 

Turkish Cerebrovascular Diseases Society 

(member of ESO and WSO)

TurkStrokeNet brings together all dedicated stroke researchers and clinicians in Turkey with the purpose of enhancing collaborative efforts for stroke research at the national and international level. The focus of research and trials embraces every aspect of stroke, including prevention, treatment and recovery, from all related disciplines. The coordinated effort of this platform will also form the backbone of national strategies that will improve and standardize quality of stroke care.



The Turkish Cerebrovascular Diseases Society, as part of its responsibilities to improve quality standards in stroke care, has now partnered with the “RES-Q (Registry of Stroke Care Quality)” program after the previous collaborations with ''SITS International’’ and “Angels Reward Program'' organizations, and invites all our members to the activities within this program as well.

Dear colleagues,

RES-Q (Registry of Stroke Care Quality) is an initiative under the guidance of ESO (European Stroke Organization) which has initially started in Europe and then spread all over the world with the primary aim to reach the recommended quality standards in centers participating in stroke care. In addition to the scientific activities carried out in the field, ensuring the required quality of stroke care in our patients is among the top priorities of the Turkish Cerebrovascular Diseases Society. The recent national stroke directive also emphasizes the importance of monitoring quality metrics in stroke units and centers. In this context, as part of our efforts to improve quality standards in stroke diagnosis and treatment, and after the collaborations with “SITS International” and “Angels Reward Program” organizations, our society has now also become a part of the “RES-Q” program.

Detailed information regarding RES-Q can be reached on the https://qualityregistry.eu website, and through the “https://www.youtube.com/watch?v=M5D3_YL8hEY” video stream. Each center can register directly to the system. The ethics committee and consent procedures for data sharing work in the light of the same principles as the SITS and Angels programs (details are available at https://turkstrokenet.com).

The quality metrics of the centers in our country will be reported to the secretariat of the Turkish Cerebrovascular Diseases Society every three months four times a year, without any patient information, and this information will be shared with the centers themselves. We are aiming to start data entry as of 01 January 2020. The centers that provide data in the first quarter will be eligible to participate in a nationwide scientific project which will be conducted in the second quarter of 2020. Details of the scientific project will be announced in the upcoming days.

We invite all our colleagues to the RES-Q program, which not only aims to improve quality standards in stroke care, but also would evolve into a scientific movement. We remind you that you can contact our secretariat for all your questions.

Ethem Murat Arsava

Moderator of TurkStrokeNet 


Turkish Cerebrovascular Diseases Society invites you to the ''SITS International’’ and “Angels Reward Program''

Dear Colleagues,

Patient entry, at least for a period, in a prospective manner, into the SITS-INTERNATIONAL (“Safe Implementation of Treatments in Stroke”) database for the purpose of collecting a broader hospital-based data on stroke clinical practice in our country is activated and encouraged by the Turkish Cerebrovascular Diseases Society (TCDS) and the Turkish Neurological Society (TNS) as from April 2019. SITS is the partner of ‘’ESO-ANGELS’’ and ‘’ANGELS award program’’ of ESO (European Stroke Organization). As of the beginning of April 2019, it is an established system with 1680 centres and 237,536 patient records. In this system, national co-coordinators are Prof. Dr. M. Akif Topçuoğlu, Prof. Dr. Özcan Özdemir, Prof. Dr. Şerefnur Öztürk and Prof. Dr. Yakup Krespi. The necessary information, including the introduction of the system, registration or activation of the registration, can be found at the following links. Please be advised that you can write your questions directly to the national co-coordinators or the TCDS society secretary.

On behalf of the local coordinators,

Prof. Dr. M. Akif Topçuoğlu, 

Head of Turkish Cerebrovascular Diseases Society 

Links and Documents

1- PRESENTATION OF ‘’SITS INTERNATIONAL’’ (to download the presentation): It is a presentation about the general introduction and possible benefits of the system. 

2- ‘’HOW CAN I BECOME A SITS CENTER?’’ or ‘’HOW CAN ACTIVATE MY REGISTRY?’’ (to download the presentation): Do not remember that your centre has a SITS record or not? You can ask the local coordinators or the national coordinator directly or check on the SITS website (http://www.sitsinternational.org/).

3- SITS INTERNATIONAL QR (to download the presentation): It contains basic information about SITS ‘’Quality Registry’’ adapted for ‘’Angels’’. 

4- SITS MOST PROTOCOL (to download the presentation): It contains the latest and the largest version of the protocol. 

5- ‘’Do I need to get an ethics committee approval anonymised for SITS?’’ ‘’Do I need patient consent?’’ Both are needed. However, non-interventional local ethics committee approval is sufficient for data sharing. You can ask the central managers whether ethics committee approval on the same issue of other centres is sufficient (for example, approval 2019/04-04 of Hacettepe University). As informed consent form, SITS's recommended consent form (Click here to download) and consent form used in Hacettepe University (Click here to download) were presented.  



MASS (Detection of Muscle Loss in Acute Stroke Patients Who Need Enteral Nutrition)

Study type: Prospective observational (National)

Clinicaltrials.gov identifier: NCT03825419 

Participating centers:

Ondokuz Mayıs University, Samsun (Coordinator)

 Ankara University, Ankara

Cumhuriyet University, Sivas

Ege University, İzmir

Gazi University, Ankara

Gaziantep University, Gaziantep

Hacettepe University, Ankara

Necmettin Erbakan University, Konya

Osmangazi University, Eskişehir

Selçuk University, Konya

Status: Recruiting patients.

TR-VENUS (Non-invasive TRanscutaneous Cervical Vagus Nerve Stimulation as a Treatment for Acute Stroke; Safety and Feasibility Study) 

 Study type: Prospective randomized (National)

Clinicaltrials.gov identifier: NCT03733431

Participating centers:

Hacettepe University, Ankara (Coordinator)

Akdeniz University, Antalya

Ankara University, Ankara

Gazi University, Ankara

Mersin University, Mersin

Necmettin Erbakan University, Konya

Ondokuz Mayıs University, Samsun 

Osmangazi University, Eskişehir

Selçuk University, Konya

Status: Recruiting patients.

IMPROVE (International Multicenter Patent Foramen Ovale & Stroke)

Study type: Prospective and restrospective observational (International)

Clinicaltrials.gov identifier: -

Participating centers:

Ankara University, Ankara (Coordinator)

Acıbadem University, İstanbul

Bakırköy  Prof. Dr. Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital, İstanbul  

Başkent University, Adana

Başkent University, Ankara

Dokuz Eylül University, İzmir

Ege University, İzmir
Florence Nightingale Hospitals, İstanbul

Gazi University, Ankara

Hacettepe University, Ankara

İstanbul University (Çapa), İstanbul

Kartal Dr. Lütfü Kırdar Training and Research Hospital, İstanbul 

Katip Çelebi University Atatürk Training and Research Hospital, İzmir Marmara University, İstanbul

Necmettin Erbakan University, Konya

Ondokuz Mayıs University, Samsun 

Osmangazi University, Eskişehir

Samsun   Training and Research Hospital, Samsun

Selçuk University, Konya

Tepecik  Atatürk Training and Research Hospital, İzmir

Status: Recruiting patients

About Us



To faciliate stroke research and clinical trial collaborations at the national and international level, and improve efforts for stroke prevention and care.



Stroke research without borders.